|
Symbol Name ID |
Apoe
apolipoprotein E MGI:88057 |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Sea-blue histiocytosis |
Allergic rhinitis |
Conjunctivitis |
Keratoconjunctivitis sicca |
Lymphadenopathy |
Splenomegaly |
Eczematoid dermatitis |
Atopic dermatitis |
Recurrent skin infections |
Autoimmunity |
Asthma |
| Disease(s) Associated with APOE | |||||||||||||||
| atopic dermatitis | |||||||||||||||
| multiple myeloma | |||||||||||||||
| sea-blue histiocytosis | |||||||||||||||
| Sjogren's syndrome |
| Mouse Phenotypes | blood vessel inflammation |
increased spleen weight |
decreased follicular B cell number |
decreased marginal zone B cell number |
increased marginal zone B cell number |
increased B cell number |
abnormal T cell number |
abnormal CD4-positive, alpha-beta T cell number |
increased T-helper 2 cell number |
increased CD4-positive, alpha-beta T cell number |
decreased macrophage cell number |
increased macrophage cell number |
abnormal B cell activation |
increased IgM level |
increased immunoglobulin level |
abnormal immune system morphology |
abnormal immune system physiology |
abnormal dendritic cell physiology |
decreased susceptibility to type IV hypersensitivity reaction |
abnormal cell-mediated immunity |
abnormal immune serum protein physiology |
decreased interferon-gamma secretion |
increased susceptibility to systemic lupus erythematosus |
increased autoantibody level |
increased anti-nuclear antigen antibody level |
increased anti-double stranded DNA antibody level |
lung inflammation |
increased susceptibility to parasitic infection |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||
| Apoetm1Unc/Apoetm1Unc | |||||||||||||||||||||||||||||
| Apoetm1.1Mae/Apoetm1.1Mae Tg(Fabp4-cre)1Rev/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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